VPM3411

Tajuk Kursus :

MIKROBIOLOGI VETERINAR I

Kod Kursus :

VPM 3411

Kredit :

3 + 1

Semester :

November

Program :

Doktor Perubatan Veterinar

Prerequisite :

None

Lecture :

Dr. Mohd Azmi Mohd Lila (Coordinator)

Objective :

At the end of the course, the student would :

acquire knowledge on materials and characteristics of agents causing diseases of veterinary importance and zoonosis
understand the relationship between animals and disease agents and the mechanisms of host infection by disease agents and vice versa, and how the host respond to the infection
be familiar with laboratory practice in isolation and identification of disease agents and principles of diagnostic techniques.
understand the immune components, phenomenon and use the knowledge to diagnose and prevent infectious diseases.

Synopsis :

This course includes general bacteriology, immunology and virology and provides sufficient basic knowledge for students to comprehend microbes and viruses as biological agents causing infectious diseases. It emphasizes on the characteristics and physical properties of agents, various modes of existence in health and disease, classification of pathogenic microorganisms, microbial genetics, metabolism and laboratory methods of isolation and identification of disease agents. The course will helps students to understand concepts and principles of the pathogenesis and epidemiology of infection taught in related courses.

Lecture Schedule :

No	Lecture Title
1	Introduction to veterinary microbiology
	*Bacteriology*
2	Bacteria structure
3	Bacteria growth
4	Bacteria nutrition and media
5	Classification of bacteria
6	Metabolism of bacteria
7	Genetics of bacteria
8	Host-parasite relationship
9	Normal Flora
10	Pathogenic properties of bacteria I
11	Pathogenic properties of bacteria II
12	Sterilization
13	Disinfection
14	Chemotherapy and antibiotic mechanism reactions
15	Antibiotic resistance mechanism
16	Fungus
17	Principles of identifying pathogenic bacteria
18	Laboratory diagnosis for bacteria infection I
19	Laboratory diagnosis for bacteria infection II
	*Virology*
20	Introduction to virology
21	Virus structure and nomenclature
22	Virus nucleic acid and replication
23	Virus growth and pathogenesis of viral infection
24	Vaccine and vaccination of viral diseases
25	Interferon and viral chemotherapy
26	Genetic manipulation in animal virology
27	Diagnostic virology
	*Immunology*
28	Introduction to immunology
29	Antigen, immunoglobulin, antigenicity, hapten and immunogenicity I
30	Antigen, immunoglobulin, antigenicity, hapten and immunogenicity II
31	Immune response mechanism
32	Multiple immune reaction mechanism
33	Hypersensitivity
34	Organ transplant and auto-immunity
35	Mucosaa dan foetus/neonatal immunity
36	Immune reactions towards infection and tumor cell I
37	Immune reactions towards infection and tumor cell II
38	Principles of vaccination

Practical Schedule :

No	Practical Title
1	Virology setrile techniques
2	Cell growth and virus in cell culture
3	Haemaagglutination (HA) and HI test, and electron microscopy
4	Egg inoculation, virus titre, TCID50 and EID50
5	Serological tests : ELISA, CFT, IFA and AGPT
6	Discussion and Tutorial
7	Smear preparation, gram staining, bacteria morphology and characteristics
8	Medium types, bacteria growth, morphology and characteristics of colony and bacteria inoculation
9	Principles of isolation, identification of bacteria from clinical specimens and acid proff staining
10	Collection, delivery and processing of clinical specimens and preparartion of pure culture
11	Biochemical test, identification of bacteria and fungi
12	Antibiotic sensitivity test and bacteria cell count

Evaluation :

           Continuous assessment      :    40%
           Practical                            :    20%
           Final exam                         :    40%
           Total                                 : 100%

Attendance :

An attendance of a minimum of 80% of the lectures and practical is required for eligibility to sit for the final semester examination

References :

Allberts, B., Bray, D., Lewis, J. Raff, M., Roberts, K. and Watson, J.D. (1989). Molecular Biology of Cell (2n Ed). Garland Publising Inc.
Castro, A.E. and Heuschele, W.P. (1992). Veterinary Diagnostic Virology: A Practioner’s Guide. Mosby Year Book Inc.
Russel, P.H. and Edington, N. (1985). Veterinary Virology, Burlington Press Ltd. , Cambridge.
Biberstein, E.L. and Zee, Y.C. (1990) Review of veterinary Microbiology, Blackwell Scientific, Boston.
Bisiping, W. and Amstsberg, (1989). Colour Atlas of Diagnosis of Bacterial Pathogens. Academic Press, London.
Quinn, P.J., Carter, M.E., Markey, B. and Carter, G.R. (1994). Clinical Microbiology. Wolfe Publishing.
Abbas. A.K., Litchman, A.H. and Pober, J.S. (1991). Cellular and Molecular Immunology. W.B. Sanders Company
Halliwell, R.E.W, and Gorman, N.T. (1989). Veterinary Clinical Immunology. W.B. Saunders Company.
Tizard, I. (1996). Veterinary Immunology: AN Introduction. W.B. Saunders Company.
Roitt, I., Brostoff, J. and Male, D.K. (1994). Immunology. Grower Medical Publishing.
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