Faculty of Veterinary Medicine

 

     

Produk Penyelidikan Komersil
 

 


 

TISSUE CULTURE FOWL POX VACCINE

 

 

Fowl pox virus causes economic losses due to high morbidity, drop in egg production and mortality.  Previously the vaccine was prepared in embryonated eggs and delivered in a wet form.  Through extensive research, researchers of the Faculty have successfully cloned a fowl pox virus that can be adapted to chick-embryo fibroblast tissue culture. 

 

The special features of this new clone are that it can grow well in tissue culture, giving a high titre and produces homogenous and high quality vaccine, which can be prepared in freeze-dried form. 

 

This technique of preparation reduces operational costs and shortens production time per dose as compared with that using embryonated eggs.  The vaccine is also more stable and has a long shelf-life.

  

This technology of fowl pox vaccine production in tissue-culture is the first to be developed in Malaysia.  It is now produced commercially by Malaysian Vaccines and Pharmaceutical Sdn. Bhd. and the product was launched in 1995.

  

For further information regarding this product, please contact aiini@vet.upm.edu.my  

 


 

UPM-V4 NEWCASTLE DISEASE VACCINE
 

Virulent Newcastle disease virus (NDV) is the world’s most lethal poultry virus.  It attacks the digestive, nervous and respiratory systems and can cause up to 100% mortality in susceptible chicken.  The disease can be controlled by vaccination which is usually administered individually, by intranasal, or intraocular routes, and the vaccine needs refrigeration.  This kind of vaccine made it impractical and difficult to administer to free range chickens.  The requirement for a ‘cold chain’ linking the manufacturer of the vaccine to the recipient chicken makes using the vaccine very expensive.
  

Researchers of the Faculty have been successful in selecting V4 strain of NDV for extreme heat resistance by sequential heat treatment and selection, and incubating the cultures up to 56oC.  The researchers also found ways to supply the vaccine on some form of food, thus avoiding the need to catch chicken individually.  This vaccine can also be administered by conventional routes.
  

The vaccine has been commercialised by Malaysian Vaccine and Pharmaceutical Sdn. Bhd. since 1993.
  

For further information regarding this product, please contact aiini@vet.upm.edu.my

 


 

INNOVATIVE WHITE SPOT SYNDROME VIRUS (WSSV) DETECTION KIT

 

Since 1992, WSSV caused major losses to the shrimp industry in many Asian countries. China recorded shrimp production loss of 80% that was equivalent to about US$1 billion. In Malaysia losses in Sabah alone were estimated to be in the region of RM 60 million. There is no treatment for the disease and the only way to avoid losses is to screen the shrimp larvae before they are introduced into the growout ponds.

  

This kit is the first that uses the advanced and automated single tube approach to detect WSSV, which is completely different from the conventional nested PCR method involving cumbersome two tubes and multiple-step procedures. This novel single tube method for shrimp virus is the first in the world and is patent pending. 

  • The innovative rapid detection system has the following advantages: Single tube - low risk of contamination, economical, fast and user friendly

  • Sensitive (can detect as low as 10 copies of viral DNA target

  • Built-in false negative and positive controls - reliable results

  • Indicates infection levels (light, moderate and heavy)

The use of this kit to detect WSSV has saved millions of Ringgits and the shrimp industry in many countries. The kit is being sold in Australia, Indonesia, India, South America, Malaysia, Sri Lanka and Thailand. 

  

For further information regarding this product, please contact shariff@vet.upm.edu.my

 

 

 

 

 

 

PENAFIAN : Universiti Putra Malaysia tidak bertanggungjawab terhadap sebarang kehilangan atau kerugian
yang dialami kerana menggunakan mana-mana maklumat yang diperolehi daripada laman web ini.

 

Laman Web Universiti Putra Malaysia Laman Web Hospital Veterinar Universiti Laman Web Perkhidmatan Makmal Veterinar Laman Web Alumni Veterinar UPM Laman Web Veternak UPM Laman Web Kelab Zoologico UPM Laman Web Kelab Sukan dan Rekreasi Veterinar Intranet Pegawai Fakulti Perubatan Veterinar Intranet Pelajar Fakulti Perubatan Veterinar
Penyelidikan di Fakulti Perubatan Veterinar Geran Penyelidikan di Fakulti Perubatan Veterinar Kepakaran Penyelidikan di Fakulti Perubatan Veterinar Pencapaian Penyelidikan di Fakulti Perubatan Veterinar Penerbitan Penyelidikan di Fakulti Perubatan Veterinar Produk Komersil Penyelidikan di Fakulti Perubatan Veterinar