IVERMECTIN: REVISITING THE OLD AND VERSATILE DRUG FOR ANIMALS
The exceptional old drug
Ivermectin (IVM) was first discovered in the late 1970s, during the end of the Vietnam War. Later on, in 1981, the use of Ivermectin in animals was recognised and approved. IVM is a versatile FDA-approved drug from the avermectin (macrocyclic lactones) group which was predominantly developed as a pioneer endectocide by Merck & Co. This mighty drug can be used in both human and veterinary medicine. Various formulations of IVM in the form of tablets, bolus, drench, pour-on, spot-on and injectables are available for livestock and pet animals. As of 31 August 2021, 29 veterinary products possessing IVM as the active ingredient have been registered by the National Pharmaceutical Agency Malaysia. All preparations with IVM require prescriptions by a licensed veterinarian in accordance with the First Schedule of Poisons Act 1952 as it is classified in Group B, Part 1 of the Poison List.
In the recent years, IVM has caught the eyes of veterinarians and drawn a vast market potential for animal health products worldwide due to its alluring characteristics such as safety profile, low adverse effects when prescribed orally and the existence of a variety of formulations for different livestock and domestic pets.